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You never know what you're gonna get." Well, that is still partially true if you dont use common sense and caution.

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Jia Zhu, Tao Peng, Christine Johnston, Khamsone Phasouk, Angela S. Koelle, Anna Wald, Harlan Robins, and Lawerence Corey Nature 497, 494-497 doi:10.1038/nature12110 () Calcium release within the cells has been shown to be fundamental for the herpes virus. JAMA: The Journal of the American Medical Association, 2011; 305 (14): 1441 DOI: 10.1001/jama.2011.420 A study of patients attending sexual health clinics in Gothenburg, Sweden, found that only four out of ten patients who had genital herpes actually knew that they had contracted the disease.

These scientists found this calcium release occurs because the hsv activates a critical cell signaling molecule called "Akt". HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression. Soc., published online July 5, 2013; doi: 10.1021/ja404008r April, 2013 | The New York Board of Health reported more cases where newborn boys contracted herpes after the Jewish ulta Orthodox practice, "metzitzah b'peh". Also reports found a third of those who did not realise that they had been infected stated typical symptoms at a follow-up visit.

This treatment (a ribozyme) has been shown to block Herpes Simplex Virus type 1 (HSV-1) infections.

Here we propose to test the ribozyme for its ability to block recurrent disease.

Most adults have contracted hsv-1, herpes simplex 1, and many are asymptomtic so they don't even know they have it. In the United States, 16 percent of adults are HSV-2 seropositive, but only 10 percent to 25 percent of persons with HSV-2 infection have recognized genital herpes. Specifically, they were: Reference: Archives of Ophthalmology Young RC, et al "Incidence, recurrence, and outcomes of herpes simplex virus eye disease in Olmsted County, Minnesota, 1976-2007: The effect of oral antiviral prophylaxis" Arch Ophthalmol 2010; 128(9): 1178-1183.